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Mysterious Disease Outbreaks That Were Never Solved

Sweating sicknesses, New World epidemics, and other strange clusters of illness with no clear cause.

As the past few years have painfully made clear, infectious diseases remain one of humanity’s greatest perils. It only took weeks for scientists to identify the cause of the covid-19 pandemic—a previously unknown species of coronavirus—but there have been plenty of outbreaks, past and present, whose true cause isn’t so obvious. Here are six mysterious outbreaks that remain unsolved.

A version of this story was originally published April 2, 2021.

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